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Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research) ; 13(7):898-905, 2022.
Article in English | Academic Search Complete | ID: covidwho-2111780

ABSTRACT

Aim: To investigate the importance of the CBC, derived parameters, and morphology of peripheral blood cells in Covid-19 patients. Material and methods: According to their symptoms, patients were classified as asymptomatic, mild, or moderate-severe. This research included all paediatric and adult patients who had two CBC samples available (one at admission and another during discharge) throughout their hospital stay. Those who were already undergoing therapy for their cancer, haematological illness, liver disease, or chronic lung disease were not allowed to participate. Results: Patients' ages varied from 8 to 71. The patients' average age was 36.15±14.58 years. Sixty percent of research participants were male, making up a sex ratio of 1.5:1. (M: F). The average white blood cell count was 6.87±3.51 x109/L, the average red blood cell count was 4.61±0.88 x106/microL, and the average haemoglobin level was 12.80±2.15 g/dl upon admission. The average absolute neutrophil count was 3.81±3.46x109/L, the average absolute lymphocyte count was 2.31±1.40x109/L, the average absolute monocyte count was 0.38±0.31x109/L, and the average absolute eosinophil count was 0.15±0.18x109/L. Overall, the average number of platelets per microliter of blood was 149.21± 80.25. Neutrophil to lymphocyte ratio (NLR) at admission was 3.806;platelet to lymphocyte ratio (PLR) was 116.32±13.1;lymphocyte to monocyte ratio (LMR) was 8.91±5.25, and derivative neutrophil to lymphocyte ratio (d-NLR) was 2.61±1.36. Twenty (40%) of the patients were asymptomatic at admission, while 44% had mild symptoms, and 16% required oxygen and ventilator support due to moderate to severe symptoms. The RT-PCR test was positive for all of the patients examined. There was a noteworthy shift in both the mean WBC and mean platelet counts after the follow-up evaluation. No correlation was seen between clinical state on admission and any of the other CBC measures (p>0.05). Conclusion: The significance of CBC values and morphological inspection of the peripheral blood smear at baseline and subsequent assessment is highlighted in the research. [ FROM AUTHOR]

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